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Osmosis Jones   2001             PG, 90 min. Genre: Comedy Director: Bobby Farrelly, Peter Farrelly   Cast: Bill Murray, Chris Rock, Laurence Fishburne, David Hyde Pierce, Brandy Norwood, William Shatner, Molly Shannon, Chris Elliott, Joel Silver, Elena Franklin   When an out-of-shape construction worker, Frank Pepperidge (Bill Murray), contracts a lethal virus, forces within his body—led by Osmosis Jones (Chris Rock) and Drix (David Hyde Pierce)—rush to fight off the virus, Thrax (Laurence Fishburne), that threatens Frank's life.